哺乳动物颌下腺中的激肽释放酶、类胰蛋白酶和淀粉酶。
Kallikrein, trypsin-like proteases and amylase in mammalian submaxillary glands.
作者信息
Bhoola K D, Dorey G
出版信息
Br J Pharmacol. 1971 Dec;43(4):784-93. doi: 10.1111/j.1476-5381.1971.tb07214.x.
Abstract
- The tissue concentration of kallikrein, trypsin-like proteases and amylase has been determined in the submaxillary glands of the cat, dog, rabbit, rat, hamster and guinea-pig.2. Submaxillary gland extracts of the six species showed a wide variation in kallikrein content. The esterase activity in the extracts, however, did not correlate with the kininogenase activity of kallikrein. Both activities in each of the six species were affected by proteinase inhibitors but not in the same way.3. Evidence is presented which indicates that trypsin-like proteases similar to those described in the rat, also occur in the hamster and cat submaxillary glands.4. An even greater spread of amylase activity was observed between the species.5. The assumption that mammalian submaxillary kallikreins are identical proteins is questioned.
摘要
已测定猫、狗、兔、大鼠、仓鼠和豚鼠颌下腺中激肽释放酶、类胰蛋白酶和淀粉酶的组织浓度。
这六个物种的颌下腺提取物中激肽释放酶含量差异很大。然而，提取物中的酯酶活性与激肽释放酶的激肽原酶活性并不相关。六种物种各自的这两种活性都受到蛋白酶抑制剂的影响，但方式不同。
有证据表明，与大鼠中描述的类似的类胰蛋白酶也存在于仓鼠和猫的颌下腺中。
在不同物种之间观察到淀粉酶活性的差异更大。
关于哺乳动物颌下激肽释放酶是相同蛋白质的假设受到质疑。
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[On the esterase effects of kallikrein and trypsin and their inhibition by kallikrein-and trypsin inhibitors].[关于激肽释放酶和胰蛋白酶的酯酶作用及其受激肽释放酶和胰蛋白酶抑制剂的抑制作用]
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[Spectrophotometric determination of kallikrein and its inactivators].[分光光度法测定激肽释放酶及其灭活剂]
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The mechanism of enzyme secretion by the cell. I. Storage of amylase in the zymogen granules of the rat-parotis gland.细胞分泌酶的机制。I. 淀粉酶在大鼠腮腺腺泡细胞酶原颗粒中的储存。
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