Weldon D A, Smith C J
Physiol Behav. 1979 Jul;23(1):159-65. doi: 10.1016/0031-9384(79)90137-9.
Bilateral lesions of the superior colliculus were produced in rats reared in either a restricted or complex environment. Problem solving ability in a Hebb-Williams closed field and activity in an open field were subsequently observed in conditions of either bright or dim illumination. Animals with superior colliculus lesions were deficient in problem solving ability and were hyperactive in the open field. Complex environment exposure during development increased problem solving ability and initial ambulation scores in all groups. Extent of pretectal damage and behavioral measures were significantly related for animals reared in the complex, but not in the restricted environment. There were no interactions with illumination level, suggesting that the deficits resulting from collicular lesions are not dependent upon the availability of visual cues.
在受限或复杂环境中饲养的大鼠，制作其上丘双侧损伤。随后在明亮或昏暗照明条件下，观察其在赫布 - 威廉姆斯封闭场中的问题解决能力以及在开放场中的活动情况。上丘损伤的动物在问题解决能力方面存在缺陷，且在开放场中表现为多动。发育期间暴露于复杂环境可提高所有组的问题解决能力和初始行走得分。对于在复杂环境而非受限环境中饲养的动物，顶盖前区损伤程度与行为指标显著相关。不存在与光照水平的交互作用，这表明丘损伤导致的缺陷不依赖于视觉线索的可用性。
