Biberstein E L, Kirkham C
Res Vet Sci. 1979 May;26(3):324-8.
Minimal concentrations of penicillin, ampicillin, cephalothin, chloramphenicol, tetracycline, erythromycin, nitrofurantoin, kanamycin and gentamicin inhibitory to Pasteurella haemolytica biotypes A and T were determined. They were found to be significantly higher for T than for A type strains in the case of all the antimicrobial drugs tested except the two aminoglycosides kanamycin and gentamicin, for which no differences were observed. In the case of penicillin the differences were so marked that they may be useful as a basis for biotyping P haemolytica isolates. The emergence of antibiotic-resistant strains observed in recent years, however, may limit such application.
测定了对溶血巴斯德氏菌A和T生物型具有抑制作用的青霉素、氨苄青霉素、头孢噻吩、氯霉素、四环素、红霉素、呋喃妥因、卡那霉素和庆大霉素的最低浓度。结果发现,除两种氨基糖苷类药物卡那霉素和庆大霉素未观察到差异外,在所测试的所有抗菌药物中,T型菌株的最低浓度显著高于A型菌株。就青霉素而言,差异非常明显,可用作溶血巴斯德氏菌分离株生物分型的依据。然而,近年来观察到的抗生素耐药菌株的出现可能会限制这种应用。