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复发性支气管炎患儿的肺功能

Lung function in children with recurrent bronchitis.

作者信息

Boule M, Gaultier C, Tournier G, Allaire Y, Girard F

出版信息

Respiration. 1979;38(3):127-34. doi: 10.1159/000194069.

Abstract

Lung function was studied in 29 children suffering from recurrent bronchitis (average number of bronchitis attacks per year: 4.2 +/- 0.5). Most of them (73%) were 1--7 years old. The date of exploration in relation to the last acute bronchitis was on average 6 weeks. Lung mechanics, residual functional capacity, blood gases and regional lung function were measured. Most of the children were suffering from some kind of functional disorder; alteration of lung mechanics -- increase of lung resistance (22/29) decrease of dynamic compliance (15/23); increase of functional residual capacity (6/10), non specific bronchial hypersensitivity (12/17); regional ventilatory and perfusion malfunction. These functional disorders could be the first evidence of the bronchial lesions which cause chronic obstructive bronchitis in adults.

摘要

对29名患有复发性支气管炎的儿童(每年支气管炎发作的平均次数:4.2±0.5)进行了肺功能研究。他们中的大多数(73%)年龄在1至7岁之间。与最后一次急性支气管炎相关的检查日期平均为6周。测量了肺力学、残气量、血气和肺区域功能。大多数儿童患有某种功能障碍;肺力学改变——肺阻力增加(22/29)、动态顺应性降低(15/23);功能残气量增加(6/10)、非特异性支气管高敏反应(12/17);肺区域通气和灌注功能障碍。这些功能障碍可能是导致成人慢性阻塞性支气管炎的支气管病变的首个证据。

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