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双嘧达莫治疗登革出血热

Dipyridamole in the treatment of dengue haemorrhagic fever.

作者信息

Kho L K, Wulur H, Himawan T

出版信息

Southeast Asian J Trop Med Public Health. 1979 Sep;10(3):385-8.

PMID:515801
Abstract

Clinical studies in the treatment of 54 children suffering from DHF with a combination of dipyridamole and ASA as an adjuvant of our standard therapy consisted of fluid, electrolytes, blood, plasma and plasma expanders were evaluated. Heparin was administered in cases of DIC. It appeared that dipyridamole and ASA did not change the mortality significantly, but it prevented the progress of the severity of the disease from grade I and II to grade III and IV.

摘要

对54名患有登革出血热(DHF)的儿童采用双嘧达莫和阿司匹林联合作为我们标准治疗辅助手段进行治疗的临床研究,评估内容包括液体、电解质、血液、血浆和血浆扩容剂。对于弥散性血管内凝血(DIC)病例给予肝素治疗。结果显示,双嘧达莫和阿司匹林并未显著改变死亡率,但可防止疾病严重程度从I级和II级进展至III级和IV级。

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