Roberson F C, Kishore P R, Miller J D, Lipper M H, Becker D P
Surg Neurol. 1979 Aug;12(2):161-7.
A consecutive series of 107 comatose patients with head injury was studied with regard to the proper role of serial computerized tomography for clinical management and as a research tool for studying the pathophysiology of severe head trauma. In this prospective study patients had serial CT scans on days 1, 3, 5, 7, 14, at 3 months, and at 1 year (day 1 is the day of admission). In seven instances CT scanning was responsible for detection of late intracranial lesions requiring surgical decompression two weeks to one year after injury. No surgically significant lesions were, however, detected by routine scanning on the pre-determined days in the early post-trauma period that had not already been signalled by changes in the neurological status, intracranial pressure, or volume pressure response. It is concluded that for purposes of clinical management, additional scans should be obtained in the following circumstances: 1) 1 day post-craniotomy, 2) no improvement by day 3, 3) at 2-3 weeks, and 4) at 3 months. All other scans should be obtained as needed. As a research tool, serial CT scanning is of value in studying post-traumatic hydrocephalus, delayed intracerebral hematomas, and intraventricular hemorrhage.
对107例昏迷的颅脑损伤患者进行了连续研究,以探讨系列计算机断层扫描在临床管理中的恰当作用,以及作为研究严重颅脑创伤病理生理学的研究工具。在这项前瞻性研究中,患者在入院第1天、第3天、第5天、第7天、第14天、3个月时和1年时(第1天为入院日)进行了系列CT扫描。在7例病例中,CT扫描检测到伤后两周至一年需要手术减压的晚期颅内病变。然而,在创伤后早期预定的日子里,通过常规扫描未检测到任何具有手术意义的病变,而这些病变在神经状态、颅内压或容积压力反应方面均未出现异常变化。得出的结论是,为了临床管理的目的,在以下情况下应进行额外的扫描:1)开颅术后第1天,2)第3天无改善,3)2 - 3周时,4)3个月时。所有其他扫描应根据需要进行。作为一种研究工具,系列CT扫描在研究创伤后脑积水、迟发性脑内血肿和脑室内出血方面具有价值。