Groothuis G, van Miert A S
Tijdschr Diergeneeskd. 1979 Nov 15;104(22):886-7.
Significantly increased levels of ampicillin were recorded in the serum of nine normal dwarf goats following injection of ampicillin trihydrate (Penbritin, 20 mg per kg of body weight) into the lateral cervical muscles compared with injection into the gluteal region (semimembranosus muscle). The differences observed serve to emphasize the fact that more attention should be paid to the effect of the site of intramuscular injection on the biological availability of the drug, with particular reference to studies on clinical effectiveness.
将三水合氨苄西林（青霉素V，每千克体重20毫克）注射到9只正常矮山羊的颈外侧肌肉中后，与注射到臀区（半膜肌）相比，血清中氨苄西林水平显著升高。观察到的差异凸显了这样一个事实，即应更加关注肌肉注射部位对药物生物利用度的影响，尤其是在临床疗效研究方面。
