Salmon J, Coussediere D, Cousty C, Delaroff V, Raynaud J P
Steroids. 1979 Oct;34(4):381-400. doi: 10.1016/0039-128x(79)90101-6.
Reference compounds for the subsequent identification of the metabolites of the potent estrogen, moxestrol (R 2858) , in various species were isolated from the bile of phenobarbital pretreated rats or obtained via enzymatic hydroxylation by microorganisms. A few of them were prepared by chemical synthesis. The structures of all these compounds were determined by physical and chemical methods.
用于后续鉴定强效雌激素莫昔司琼(R 2858)在各种物种中代谢产物的参考化合物,是从经苯巴比妥预处理的大鼠胆汁中分离得到的,或者是通过微生物的酶促羟基化作用获得的。其中一些是通过化学合成制备的。所有这些化合物的结构均通过物理和化学方法确定。