Smith J S, Whitelaw D M
Can Med Assoc J. 1971 Oct 23;105(8):816-8 passim.
To determine whether the level of hemoglobin declines with age a group of 92 aged males averaging 81 years was carefully examined to exclude disease likely to cause anemia or polycythemia. Arterial blood was drawn from each patient before he was allowed out of bed in the morning to avoid the hemoconcentrating effect of the erect posture. The mean hemoglobin concentration was 12.9 +/- 1.5 g.% and the values were distributed normally. There was a decline of hemoglobin concentration with age which is probably nonlinear since it becomes more marked in the very old. The decline is thought to be part of the aging process and not a manifestation of disease.
为了确定血红蛋白水平是否会随着年龄增长而下降，对一组平均年龄为81岁的92名老年男性进行了仔细检查，以排除可能导致贫血或红细胞增多症的疾病。在每位患者早晨起床前采集动脉血，以避免直立姿势造成的血液浓缩效应。平均血红蛋白浓度为12.9 +/- 1.5 g.%，数值呈正态分布。血红蛋白浓度随年龄下降，这可能是非线性的，因为在非常年老的人群中这种下降更为明显。这种下降被认为是衰老过程的一部分，而非疾病的表现。
