Smiller R R, Shurygina E A, Tiutiunova A M, Il'inskaia E G
Vopr Onkol. 1979;25(11):68-72.
As a result of examining the urine excretion of 17-OCS, 17-KS, estrogens and the concentration of protein bound iodine and butanolextractable iodine in blood of patients with benign and malignant ovarian tumors, there were found some deviations from the normal hormonal balance in all these patients. These deviations were manifested in a delayed transformation of cortisol to cortisone, in a shifted androgeno-estrogenic balance toward estrogen active fractions, and in the reduced production of thyroid hormones. In ovarian cancer, however, these changes were manifested to a greater extent.
通过检测患有良性和恶性卵巢肿瘤患者的尿液中17-氧皮质类固醇、17-酮类固醇、雌激素以及血液中蛋白结合碘和丁醇可提取碘的浓度，发现所有这些患者的激素平衡均存在一些偏离正常的情况。这些偏离表现为皮质醇向可的松的转化延迟、雄激素 - 雌激素平衡向雌激素活性部分偏移以及甲状腺激素分泌减少。然而，在卵巢癌患者中，这些变化表现得更为明显。
