Hofstädter F, Schullian W, Unterkircher S
Wien Klin Wochenschr. 1979 Nov 23;91(22):748-51.
Thyroid aspiration biopsy is a valuable complementary method for the examination of an enlarged thyroid gland--especially of cold nodules. Undifferentiated tumours and papillary carcinomas can be recognized with great accuracy. The inability to achieve a precise distinction between atypical follicular adenoma and highly-differentiated follicular carcinoma leads to false-positive or false-negative findings--depending on the strategy of cytological evaluation used. The selective value of the method can be preserved only by accepting false-positive cytological findings; false-negative findings are rare. Aspiration biopsy and cytological examination of the thyroid gland, therefore, can make a valuable contribution towards obtaining a precise indication for the surgical treatment of cold nodules of the thyroid.
甲状腺细针穿刺活检是检查甲状腺肿大尤其是冷结节的一种有价值的辅助方法。未分化肿瘤和乳头状癌能够被高度准确地识别。无法精确区分非典型滤泡性腺瘤和高分化滤泡癌会导致假阳性或假阴性结果,这取决于所采用的细胞学评估策略。只有接受假阳性的细胞学结果,该方法的筛选价值才能得以保留;假阴性结果较为罕见。因此,甲状腺细针穿刺活检及细胞学检查对于明确甲状腺冷结节手术治疗的准确指征能做出重要贡献。