Karmanova I G, Maksimuk V F, Voronov I B, Bogoslovskiĭ M M, Demin N N
Zh Evol Biokhim Fiziol. 1979 Nov-Dec;15(6):583-9.
Suboccipital administration of the oligopeptide in a dose 15 or 20 micrograms/kg evokes within 15--20 min the electrographic (delta-sleep) and behavioural sleep in cats and albino rats. Oligopeptide administration significantly increases threshold reactions of EEG to sonic stimulation. Significant delay (for 50--90 min) of the development of paradoxical sleep was observed which is considered as a manifestation of inhibition of further development of sleep mechanisms due to the effect of neuropeptide. The data obtained indicate that natural sleep is not identical to that induced by the neuropeptide.
以15或20微克/千克的剂量在猫和白化大鼠的枕下给药该寡肽，会在15 - 20分钟内引发脑电图（δ睡眠）和行为睡眠。给予寡肽显著增加了脑电图对声音刺激的阈值反应。观察到反常睡眠的发展显著延迟（50 - 90分钟），这被认为是由于神经肽的作用抑制了睡眠机制进一步发展的表现。所获得的数据表明，自然睡眠与神经肽诱导的睡眠不同。
