Koehler K, Seminario I
Acta Psychiatr Scand. 1979 Oct;60(4):347-54. doi: 10.1111/j.1600-0447.1979.tb00284.x.
Recently, provisional research criteria for "schizo-affective" and related psychoses were published by the St. Louis Group. These rigorous criteria were modified and expanded for purposes of the present study in order to analyze the case records of 83 first admissions of Schneider-positive schizophrenics, that is, those with first rank symptoms, hospitalized in a strongly Schneider-oriented German University Clinic during the period 1962-1971. Research diagnosable "schizo-affective" disorder was thus found in 27.7% (23 cases) of these patients; 12 of the 23 satisfied "full" affective research criteria for depression or mania, whereas 11 fulfilled "adjusted" affective criteria geared to cover more "labile" mixed mood states. Moreover, 48.2% (40 cases) and 25.3% (21 cases) of the sample were research-positive for "schizophreniform" illness and "atypical schizophrenia" respectively. Findings such as these suggest that "first rank" schizophrenia, as routinely diagnosed in Germany, may not be all that homogeneous a clinical entity.
最近，圣路易斯小组公布了“分裂情感性”及相关精神病的临时研究标准。为了本研究的目的，对这些严格的标准进行了修改和扩展，以便分析1962年至1971年期间在一所强烈倾向于施奈德理论的德国大学诊所住院的83例首次入院的施奈德阳性精神分裂症患者（即有一级症状的患者）的病例记录。结果发现，这些患者中有27.7%（23例）患有研究可诊断的“分裂情感性”障碍；23例中有12例符合抑郁或躁狂的“完全”情感研究标准，而11例符合旨在涵盖更“不稳定”混合情绪状态的“调整后”情感标准。此外，样本中分别有48.2%（40例）和25.3%（21例）的患者“精神分裂症样”疾病和“非典型精神分裂症”研究呈阳性。诸如此类的发现表明，在德国常规诊断的“一级”精神分裂症，可能并非一个如此同质化的临床实体。
