Bongartz E B, Bamberg M, Nau H E, Schmitt G, Bayindir C
Acta Neurochir (Wien). 1979;50(1-2):117-25. doi: 10.1007/BF01813556.
Twenty-eight children with medulloblastoma (19 boys and 9 girls) were treated at the Departments of Neurosurgery and Radiotherapy in Essen between 1969 and 1977, and were followed prospectively after surgical treatment and postoperative irradiation. Because different radiation techniques had been used, these patients were divided into two groups, one given a limited irradiation volume and the other irradiation of the entire central nervous system. The results obtained in the former group were inferior to those in the latter. All living patients in the seond group are in good condition. Special attention is paid to the technique of irradiation and the factors which may influence prognosis. Even after the relatively short follow up period of one to five years, it may be concluded that high-dose irradiation of the entire central nervous system considerably improved the prognosis of medulloblastoma.
1969年至1977年间，埃森市神经外科和放疗科对28例髓母细胞瘤患儿（19例男孩，9例女孩）进行了治疗，并在手术治疗和术后放疗后进行了前瞻性随访。由于采用了不同的放疗技术，这些患者被分为两组，一组给予有限的照射体积，另一组照射整个中枢神经系统。前一组的结果不如后一组。第二组所有存活患者情况良好。特别关注放疗技术以及可能影响预后的因素。即使在相对较短的1至5年随访期后，也可以得出结论，对整个中枢神经系统进行高剂量放疗可显著改善髓母细胞瘤的预后。
