Taavitsainen M
Ann Clin Res. 1979 Aug;11(4):140-5.
The hepatobiliary transit of 99mTc-diethyl-IDA was studied in 50 cases of acute cholecystitis. The intrahepatic transit was characterized by the liver mean transit time of the tracer. The extrahepatic passage through the biliary tract was assessed from a series of scintigrams. The data were classified according to previously obtained knowledge of normal and pathological states of the liver and the biliary tract. (Normal liver mean transit time less than or equal to 70 minutes, normal appearance-time of the tracer in the biliary tract less than or equal to 15 minutes and in the intestine less than or equal to 20 minutes, no retention of the tracer in the biliary tract in cases of later appearance-times). Abnormal hepatobiliary transit of the tracer was recorded in 27 cases; it was retarded at the intrahepatic level in 11 cases, at the gallbladder neck in 3 cases, distally in the biliary tract in 12 cases, and a tight extrahepatic obstruction was seen in 1 case. In consequence, acute cholecystitis is often associated with disturbed hepatobiliary function. The functional changes in acute cholecystitis were similar to those associated with other hepatobiliary disorders of either intrahepatic or extrahepatic origin.
对50例急性胆囊炎患者进行了99mTc - 二乙基亚氨基二乙酸（99mTc - diethyl - IDA）的肝胆转运研究。肝内转运以示踪剂在肝脏的平均转运时间为特征。通过一系列闪烁扫描图评估示踪剂通过胆道的肝外通道。根据先前获得的肝脏和胆道正常及病理状态的知识对数据进行分类。（正常肝脏平均转运时间小于或等于70分钟，示踪剂在胆道中的出现时间小于或等于15分钟，在肠道中小于或等于20分钟，出现时间较晚的情况下示踪剂在胆道中无滞留）。27例记录到示踪剂的肝胆转运异常；其中11例在肝内水平延迟，3例在胆囊颈部延迟，12例在胆道远端延迟，1例可见肝外紧密梗阻。因此，急性胆囊炎常伴有肝胆功能紊乱。急性胆囊炎的功能变化与其他肝内或肝外源性肝胆疾病相关的变化相似。
