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[大鼠不同严重程度烧伤后活体微循环与血液流变学变化的对比研究]

[Comparative study of intravital microcirculation and hemorheological changes following burn injury of different severity in rats].

作者信息

Shtyklino Iu M, Udovichenko V I

出版信息

Biull Eksp Biol Med. 1979 Sep;88(9):284-6.

PMID:519018
Abstract

It was shown in experiments on rats that burn injury is followed by microcirculatory disturbances, hemoconcentration and increasing blood viscosity that is especially pronounced in the vessels with low blood pressure. The microcirculatory changes in the mesentery correlated with the in vitro investigated dynamic viscosity and blood composition. The disturbances were more pronounced after severe burn followed by a mortal shock than after moderate burn without fatal consequences. This investigation confirms great importance of hemorheological changes and microcirculatory disturbances in the early period of burn disease.

摘要

在对大鼠的实验中表明,烧伤后会出现微循环障碍、血液浓缩和血液粘度增加,这在血压低的血管中尤为明显。肠系膜中的微循环变化与体外研究的动态粘度和血液成分相关。严重烧伤后发生致命性休克后的干扰比中度烧伤且无致命后果后的干扰更明显。这项研究证实了血液流变学变化和微循环障碍在烧伤疾病早期的重要性。

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