Fereberger W, Robier F P, Sailer S
Blut. 1979 Dec;39(6):399-403. doi: 10.1007/BF01008660.
From 1967 to 1978 38 patients with polycythemia vera received a long term cytostatic chemotherapy. The results of 14 patients who were given Procarbacin (Natulan) during a mean treatment time of 9 1/2 years are communicated. Two patients showed secondary tumors after 9 or 11 years respectively. The advantages and disadvantages of the various therapeutic approaches in the management of polycythemia in the literature are discussed together with our own experiences.
1967年至1978年期间,38例真性红细胞增多症患者接受了长期的细胞抑制化疗。本文报告了14例患者的治疗结果,这些患者平均接受丙卡巴肼(甲基苄肼)治疗9.5年。分别有2例患者在9年和11年后出现了继发性肿瘤。结合我们自己的经验,讨论了文献中治疗真性红细胞增多症的各种治疗方法的优缺点。