McGivern D, Hardcastle A, Millar J G, Warren D J
Clin Endocrinol (Oxf). 1979 Jul;11(1):105-9. doi: 10.1111/j.1365-2265.1979.tb03053.x.
In six normal male subjects plasma renin activity (PRA) rose progressively on standing over a 2 hour period. PRA fell to basal levels after a further 2 hours of recumbency. The rate of rise of PRA on standing was largely abolised following the application of an anti-gravity ('G') suit. Continuous monitoring of blood pressure (BP) heart rate (HR) and packed cell volume (PCV) suggest that it is the fall in effective blood volume which elicits the stimuli to renin release during changes in posture.
在6名正常男性受试者中，血浆肾素活性（PRA）在站立2小时期间逐渐升高。再平卧2小时后，PRA降至基础水平。穿着抗重力（“G”）服后，站立时PRA的升高速率基本被消除。对血压（BP）、心率（HR）和血细胞比容（PCV）的持续监测表明，在姿势改变过程中，有效血容量的下降引发了肾素释放的刺激。
