O'Sullivan J B
Diabetes Care. 1979 Mar-Apr;2(2):85-90. doi: 10.2337/diacare.2.2.85.
Data from the epidemiologic survey in Sudbury, Massachusetts, demonstrate that the prevalence of new cases of diabetes, based on the USPHS criteria for the standard 3-h oral glucose tolerance test as originally published, was 0.7%. If a fasting blood sugar greater than or equal to 110 mg/dl had been required for those USPH diagnoses, the prevalence would have fallen to 0.28%. Further, if a peak serum insulin level of less than or greater than 60 microM/ml had been required, the original prevalence rate would have dropped to 0.02%. Data from a prospeh criteria for diabetes indicate by life table analyses that 41% show further deterioration of carbohydrate control over the first 13 yr of the study when the fasting blood sugar was less than 110 mg/dl in the initial diagnostic test and 82% when the fasting blood sugar was greater than or equal to 110 mg/dl. The relationship of fasting blood glucose to later decompensation proved to be a continuous one without evidence of a threshold effect. The implications of both of these studies for diagnostic criteria, particularly recent proposals, is discussed.
马萨诸塞州萨德伯里的流行病学调查数据表明，根据最初公布的美国公共卫生署标准3小时口服葡萄糖耐量试验，糖尿病新发病例的患病率为0.7%。如果那些美国公共卫生署的诊断要求空腹血糖大于或等于110毫克/分升，患病率将降至0.28%。此外，如果要求血清胰岛素峰值水平低于或高于60微摩尔/毫升，原来的患病率将降至0.02%。一项针对糖尿病前瞻性标准的数据通过生命表分析表明，在研究的前13年中，当初始诊断测试中空腹血糖低于110毫克/分升时，41%的患者碳水化合物控制情况进一步恶化；当空腹血糖大于或等于110毫克/分升时，这一比例为82%。空腹血糖与后期失代偿之间的关系被证明是连续的，没有阈值效应的证据。讨论了这两项研究对诊断标准的影响，特别是近期的提议。
