Deformed optic nerves in coisogenic albino and pigmented C57BL/6J--c2j mice.

The incidence of deformed optic nerve (DON) in C57 BL/6J--c2J mice is similar to that of a pigmented substrain of Long-Evans rats and much less than that of an albino substrain of Sprague Dawley rats. C57BL/6J--c2J albinos have no more DON than do coisogenic black mice. This suggests that albinism is not a factor in DON and that observed DON in Sprague Dawley rats are strain or substrain characteristics.