Stritoni P, Daliento L, Fasoli G, Schivazappa L, Chioin R, Fusaro A, Casarotto D, Bortolotti U, Valente M, Thiene G
G Ital Cardiol. 1979;9(9):1001-16.
The clinical, surgical and pathological features of 13 patients (3 males, 10 females) with cardiac myxoma are reported. Eleven masses were situated in the left atrium and 2 in the right one. The incidence of signs and symptoms usually ascribed to cardiac myxoma is evaluated. Particular emphasis is given to embolization phenomenon which occurred in 3 patients with villous-surfaced tumors. The results of phonocardiographic, echocardiographic and isotopic angioscintigraphic examination are illustrated and the use of these incruent investigations is highly recommanded. Final diagnosis may be achieved by cardiac catheterization and angiocardiography. Successful surgical excision was carried out in 12 patients. Structural profile of atrial myxoma is discussed. Particular attention is given to the surface of the tumors (smooth or villous), to the pseudovascular structures on the light microscopy and to the endotelial like features, together with secretory activity of the myxoma cells, on the electron microscopy. The morphologic findings support the neoplastic origin of the myxoma. The distinction between embolization and malignant metastasis is underlined.
报告了13例心脏黏液瘤患者（3例男性，10例女性）的临床、手术和病理特征。11个肿块位于左心房，2个位于右心房。评估了通常归因于心脏黏液瘤的体征和症状的发生率。特别强调了3例表面呈绒毛状肿瘤的患者发生的栓塞现象。展示了心音图、超声心动图和同位素血管闪烁造影检查的结果，并强烈推荐使用这些检查方法。最终诊断可通过心导管检查和心血管造影实现。12例患者成功进行了手术切除。讨论了心房黏液瘤的结构特征。特别关注肿瘤的表面（光滑或绒毛状）、光镜下的假血管结构以及电镜下的内皮样特征和黏液瘤细胞的分泌活性。形态学发现支持黏液瘤的肿瘤起源。强调了栓塞与恶性转移之间的区别。
