Schweppe K W, Beller F K
Geburtshilfe Frauenheilkd. 1979 Dec;39(12):1024-32.
The controversy of prophylactic oophorectomy is discussed. The literature is reviewed and the personal observations of the last 20 years are described. The following conclusions are drawn: The operative risk is not increased by oophorectomy. Hysterectomy does not diminish the function of the remaining ovaries. Pathology of the ovaris is not influenced by hysterectomy. The incidence of ovarian cancer is the same in patients following hysterectomy at it is in patient's without hysterectomy. A review of our cases showed that 700 prophylactic oophorectomies are necessary to prevent one case of ovarian cancer. The later occurence of menopause is an argument against prophylactic oophorectomy prior to age 55.
讨论了预防性卵巢切除术的争议。回顾了相关文献并描述了过去20年的个人观察结果。得出以下结论:卵巢切除术不会增加手术风险。子宫切除术不会削弱剩余卵巢的功能。子宫切除术不会影响卵巢的病理状况。子宫切除术后患者的卵巢癌发病率与未进行子宫切除术的患者相同。对我们的病例进行回顾显示,预防一例卵巢癌需要进行700例预防性卵巢切除术。绝经延迟是反对在55岁之前进行预防性卵巢切除术的一个理由。