Marti J J, Ammann C, de Gasparo D
Geburtshilfe Frauenheilkd. 1979 Dec;39(12):1069-78.
Preoperative administration of 15 mls of the antacid Andursil to women undergoing surgical procedures in GA during pregnancy does reduce the risk of aspiration pneumonitis (Mendelson-Syndrome) from 1:3,5 to 1:15,5. The data show that the number of risk patients is increased in early stages of pregnancy and--surprisingly--in patients undergoing elective surgery. Pains and costs of prophylactic antacids are negligible. Neonates of LSCS patients receiving an antacid are not at an increased risk. As a conclusion the prophylactic administration of oral antacids to all pregnant women having a GA is recommended.
对孕期接受全身麻醉手术的女性术前给予15毫升抗酸剂安杜西林，确实可将吸入性肺炎（门德尔松综合征）的风险从1:35降低至1:155。数据显示，妊娠早期以及——令人惊讶的是——接受择期手术的患者中，风险患者数量有所增加。预防性使用抗酸剂的疼痛和费用可忽略不计。接受抗酸剂的剖宫产患者的新生儿并无风险增加。因此，建议对所有接受全身麻醉的孕妇预防性给予口服抗酸剂。
