痰液中嗜酸性粒细胞的临床评估。
Clinical evaluation of eosinophils in the sputum.
作者信息
Vieira V G, Prolla J C
出版信息
J Clin Pathol. 1979 Oct;32(10):1054-7. doi: 10.1136/jcp.32.10.1054.
The sputum differential eosinophil/neutrophil count was done in 384 patients using Leishman staining. The patients were distributed in four groups: bronchial asthma (197 patients); chronic bronchitis with wheezing (45 patients); chronic bronchitis and/or emphysema without wheezing (73 patients); other pulmonary diseases (64 patients). Eosinophils were present in patients from all groups but more frequently (P less than 0.001) in asthma: 142 (72%) of 197 patients. In bronchial asthma and chronic bronchitis with wheezing the percentages of eosinophils were more frequently (P less than 0.001) above 80%: 57% and 58% of the patients respectively. The other two groups had more cases with 19% or less eosinophils. There is no percentage level specific for asthma but levels above 80% of eosinophils are strongly suggestive of asthma or of chronic bronchitis with wheezing.
对384例患者采用利什曼染色法进行痰液嗜酸性粒细胞/中性粒细胞分类计数。患者分为四组：支气管哮喘（197例）；喘息性慢性支气管炎（45例）；无喘息的慢性支气管炎和/或肺气肿（73例）；其他肺部疾病（64例）。所有组的患者痰液中均有嗜酸性粒细胞，但哮喘患者中更为常见（P<0.001）：197例患者中有142例（72%）。在支气管哮喘和喘息性慢性支气管炎中，嗜酸性粒细胞比例超过80%的情况更为常见（P<0.001），分别占患者的57%和58%。另外两组中嗜酸性粒细胞比例为19%或更低的病例更多。哮喘没有特定的百分比水平，但嗜酸性粒细胞比例高于80%强烈提示哮喘或喘息性慢性支气管炎。
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