Coulomb M, Faure H, Aguettaz L, Brambilla C, Parent B, Vincent J
J Radiol. 1979 Oct;60(10):591-603.
The authors try to define the criteria for the diagnosis of this unusual variety of bronchio pulmonary adenocarcinoma. They studied only 9 patients, 8 of whom had surgery which allowed to make a correlation between X-ray and morphological findings. The pathologist encountered the usual problems in the diagnosis of a primitive tumor since some metastasis have the same macroscopic and microscopic aspect. The relation between the radiographic image and the anatomical findings is emphasised. From a symptomatic and radiological point of view, the most frequent distinction was between the opaque round intra-pulmonary image and the chronic alveolar opacity. Other radiological types occurrence less frequently, such as the nodular or the hollowed type. The authors emphasize the pronostic importance of distinguishing the localized form, with a generally good prognosis following surgery, form the diffused form, which have a very poor prognosis. Even under the best of conditions, a radiological study must be supported by both surgery and pathology to be sure that the tumor in question is, in fact, strictly localized. The histogenesis of bronchio-alveolar carcinoma is briefly discussed in a study of histology and pathology.
作者试图界定这种不寻常类型的支气管肺腺癌的诊断标准。他们仅研究了9例患者，其中8例接受了手术，这使得能够将X线检查结果与形态学发现进行关联。由于一些转移灶具有相同的宏观和微观表现，病理学家在诊断原发性肿瘤时遇到了常见问题。文中强调了放射影像与解剖学发现之间的关系。从症状和放射学角度来看，最常见的区别在于肺内不透明圆形影像与慢性肺泡性混浊之间。其他放射学类型如结节型或空洞型出现频率较低。作者强调区分局部型（手术预后通常良好）与弥漫型（预后极差）在预后方面的重要性。即使在最佳条件下，放射学研究也必须得到手术和病理学的支持，以确保所讨论的肿瘤实际上严格局限。在组织学和病理学研究中简要讨论了细支气管肺泡癌的组织发生。
