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Effect of acetoxycycloheximide and of an acetoxycycloheximide-puromycin mixture on cerebral protein synthesis and memory in mice.乙酰氧基环己酰亚胺及乙酰氧基环己酰亚胺-嘌呤霉素混合物对小鼠脑蛋白质合成及记忆的影响。
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Memory in mice analyzed with antibiotics. Antibiotics are useful to study stages of memory and to indicate molecular events which sustain memory.用抗生素分析小鼠的记忆。抗生素对于研究记忆阶段以及揭示维持记忆的分子事件很有用。
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3
Loss of memory in mice as related to regional inhibition of cerebral protein synthesis.
Tex Rep Biol Med. 1966 Spring;24(1):3-19.
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Brain Res. 1967 Feb;4(1):44-51. doi: 10.1016/0006-8993(67)90147-3.
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Further studies on the effects of blocking agents on protein synthesis in goldfish brain.关于阻断剂对金鱼脑蛋白质合成影响的进一步研究。
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Stages of memory in mice treated with acetoxycycloheximide before or immediately after learning.在学习前或学习后立即用乙酰氧基环己酰亚胺处理的小鼠的记忆阶段。
Proc Natl Acad Sci U S A. 1966 Aug;56(2):730-5. doi: 10.1073/pnas.56.2.730.

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Persistent transcriptional programmes are associated with remote memory.持久的转录程序与远程记忆有关。
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Critical period of memory enhancement during taste avoidance conditioning in Lymnaea stagnalis.椎实螺味觉回避条件反射过程中记忆增强的关键期
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The role of protein synthesis in memory consolidation: progress amid decades of debate.蛋白质合成在记忆巩固中的作用：历经数十年争论后的进展。
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Protein synthesis required for long-term memory is induced by PKC activation on days before associative learning.长期记忆所需的蛋白质合成是在联想学习前几天由蛋白激酶C激活诱导产生的。
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The fine structure of puromycin-induced changes in mouse entorhinal cortex.嘌呤霉素诱导的小鼠内嗅皮质变化的精细结构
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8
[Learning and memory--experiments with the honey bee].
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9
Further observations on restoration of memory lost after treatment with puromycin.关于嘌呤霉素治疗后失忆恢复情况的进一步观察
Yale J Biol Med. 1969;42(3-4):235-40.
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Studies on memory: distribution of peptidyl-puromycin in subcellular fractions of mouse brain.记忆研究：肽基嘌呤霉素在小鼠脑亚细胞组分中的分布
Proc Natl Acad Sci U S A. 1971 Jan;68(1):26-8. doi: 10.1073/pnas.68.1.26.

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ROLE OF THE GENETIC MESSAGE IN POLYRIBOSOME FUNCTION.遗传信息在多核糖体功能中的作用。
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BREAKDOWN AND REASSEMBLY OF RAT LIVER ERGOSOMES AFTER ADMINISTRATION OF ETHIONINE OR PUROMYCIN.给予乙硫氨酸或嘌呤霉素后大鼠肝脏微粒体的分解与重新组装
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LOSS OF RECENT MEMORY IN MICE AS RELATED TO REGIONAL INHIBITION OF CEREBRAL PROTEIN SYNTHESIS.小鼠近期记忆丧失与大脑蛋白质合成的区域抑制有关。
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Proc Natl Acad Sci U S A. 1964 Oct;52(4):1030-5. doi: 10.1073/pnas.52.4.1030.
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EFFECT OF CYCLOHEXIMIDE ON RIBOSOMAL AGGREGATES ENGAGED IN PROTEIN SYNTHESIS IN VITRO.环己酰亚胺对体外参与蛋白质合成的核糖体聚集体的影响。
Biochim Biophys Acta. 1964 Jul 22;87:525-8. doi: 10.1016/0926-6550(64)90131-8.
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CYCLOHEXIMIDE: ASPECTS OF INHIBITION OF PROTEIN SYNTHESIS IN MAMMALIAN CELLS.环己酰亚胺：哺乳动物细胞中蛋白质合成抑制的相关方面
Science. 1964 Dec 11;146(3650):1474-6. doi: 10.1126/science.146.3650.1474.
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PUROMYCIN INHIBITION OF PROTEIN SYNTHESIS: INCORPORATION OF PUROMYCIN INTO PEPTIDE CHAINS.嘌呤霉素对蛋白质合成的抑制作用：嘌呤霉素掺入肽链的过程。
Proc Natl Acad Sci U S A. 1964 Apr;51(4):585-92. doi: 10.1073/pnas.51.4.585.
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INHIBITION OF PROTEIN SYNTHESIS IN VITRO BY CYCLOHEXIMIDE.环己酰亚胺对体外蛋白质合成的抑制作用。
Nature. 1963 Nov 16;200:675-6. doi: 10.1038/200675a0.
9
INHIBITION OF THE SYNTHESIS OF PROTEIN IN INTACT ANIMALS BY ACETOXYCYCLOHEXIMIDE AND A METABOLIC DERANGEMENT CONCOMITANT WITH THIS BLOCKADE.乙酰氧基环己酰亚胺对完整动物体内蛋白质合成的抑制作用以及伴随这种阻断的代谢紊乱。
Biochem Pharmacol. 1963 Aug;12:855-65. doi: 10.1016/0006-2952(63)90116-3.
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Memory in mice as affected by intracerebral puromycin.脑内嘌呤霉素对小鼠记忆的影响
Science. 1963 Jul 5;141(3575):57-9. doi: 10.1126/science.141.3575.57.

Effect of acetoxycycloheximide and of an acetoxycycloheximide-puromycin mixture on cerebral protein synthesis and memory in mice.

作者信息

Flexner L B, Flexner J B

出版信息

Proc Natl Acad Sci U S A. 1966 Feb;55(2):369-74. doi: 10.1073/pnas.55.2.369.

DOI:10.1073/pnas.55.2.369
PMID:5220953
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC224151/
Abstract
摘要