A quantitative analysis of the binding of N-acyl derivatives of alpha-aminoamides by alpha-chymotrypsin.
作者信息
Hamilton C L, Niemann C, Hammond G S
出版信息
Proc Natl Acad Sci U S A. 1966 Mar;55(3):664-9. doi: 10.1073/pnas.55.3.664.
Abstract
摘要
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A quantitative analysis of the binding of N-acyl derivatives of alpha-aminoamides by alpha-chymotrypsin.α-胰凝乳蛋白酶对α-氨基酰胺的N-酰基衍生物结合作用的定量分析。
Proc Natl Acad Sci U S A. 1966 Mar;55(3):664-9. doi: 10.1073/pnas.55.3.664.
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The binding of inhibitors to alpha-chymotrypsin at alkaline pH.在碱性pH条件下抑制剂与α-糜蛋白酶的结合。
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Specificity in deacylation of acyl-alpha-chymotrypsins.酰基-α-胰凝乳蛋白酶脱酰作用的特异性
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Irreversible enzyme inhibitors. 113. Proteolytic enzymes. 3. Active-site-directed irreversible inhibitors of alpha-chymotrypsin derived from phenoxyacetamides with an N-fluorosulfonylphenyl substituent.
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Conformation and activity of chymotrypsin: the pH-dependent, substrate-induced proton uptake.胰凝乳蛋白酶的构象与活性：pH 依赖性、底物诱导的质子摄取
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Evidence for an extended active center in elastase.弹性蛋白酶中存在扩展活性中心的证据。
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Theories of enzyme specificity and their application to proteases and aminoacyl-transfer RNA synthetases.酶特异性理论及其在蛋白酶和氨酰基转移RNA合成酶中的应用。
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Alpha-Chymotrypsin and the Nature of Enzyme Catalysis.α-胰凝乳蛋白酶与酶催化的本质
Science. 1964 Mar 20;143(3612):1287-96. doi: 10.1126/science.143.3612.1287.
2
Use of the pH-stat in kinetic studies of reactions whose products are capable of functioning as buffers.pH稳态在产物可作为缓冲剂的反应动力学研究中的应用。
Biochemistry. 1962 Mar;1:238-43. doi: 10.1021/bi00908a007.
3
INTERACTION OF AROMATIC COMPOUNDS WITH ALPHA-CHYMOTRYPSIN.芳香族化合物与α-胰凝乳蛋白酶的相互作用
Biochemistry. 1963 Jul-Aug;2:824-36. doi: 10.1021/bi00904a035.
4
Interaction of alpha-chymotrypsin with several alpha-methyl-alpha-acylamino acid methyl esters.α-胰凝乳蛋白酶与几种α-甲基-α-酰基氨基酸甲酯的相互作用。
Biochemistry. 1962 Mar;1:243-9. doi: 10.1021/bi00908a008.
5
Nitrogen analogs of representative substrates and inhibitors of alpha-chymotrypsin.α-胰凝乳蛋白酶代表性底物和抑制剂的氮类似物。
Biochim Biophys Acta. 1961 Jul 8;50:520-6. doi: 10.1016/0006-3002(61)90012-9.
6
An interpretation of the kinetic behavior of model substrates of alpha-chymotrypsin.α-胰凝乳蛋白酶模型底物动力学行为的解释
Proc Natl Acad Sci U S A. 1961 Sep 15;47(9):1341-55. doi: 10.1073/pnas.47.9.1341.
7
An electrophilic mechanism in the chymotrypsin-catalyzed hydrolysis of anilide substrates.胰凝乳蛋白酶催化酰苯胺底物水解的亲电机制。
J Am Chem Soc. 1965 Jan 5;87(1):126-7. doi: 10.1021/ja01079a027.
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