Ohta Y, Nan'no H, Fujimoto O, Fujii H, Asao H
Sangyo Igaku. 1979 Sep;21(5):433-41. doi: 10.1539/joh1959.21.433.
Somatosensory evoked responses (SERs) to mechanical (tapping) stimulation were recorded in 24 patients with occupational vibration disease, and they were compared with those recorded in 48 normal subjects. Tapping stimuli were applied on the finger, the palm and the forearm of the bilateral sides. On the other hand, SERs to electrical stimulation were recorded in 5 of the patients, and these were compared with SERs to mechanical stimulation. 1. Some peaks in 32 out of 48 SERs to mechanical stimulation on the finger were absent, and peak latencies in 10 out of the remaining 16 SERs were abnormally prolonged. On the other hand, only 2 out of 27 SERs to mechanical stimulation on the forearm were abnormal. 2. Some peaks in 27 out of 35 SERs recorded in patients with numb sensation in the fingers were absent and peak latencies in the remaining 8 SERs were abnormally prolonged. 3. With respect to the absence of peaks in SERs, P2 and N2 peaks were more frequently absent than N3 and P4 peaks. 4. Peak latencies of the SERs in the patients with occupational vibration disease were abnormally prolonged. The difference of the peak latency between the patients and the controls was statistically significant. 5. Ten SERs to mechanical stimulation and 10 SERs to electrical stimulation were recorded in 5 patients. Nine out of the 10 SERs to mechanical stimulation were abnormal, while only 2 out of the 10 SERs to electrical stimulation were observed. 6. Based on a close relationship between abnormal SERs to mechanical stimulation and the numb sensation in the finger of the patients, it was concluded that sensory disturbances in the occupational vibration disease was due to the lesion in the peripheral nerve. Therefore, SERs to mechanical stimulation can be used for detecting some localized sensory abnormality due to the lesion in the peripheral nerve.
对24例职业性振动病患者记录了对机械（轻叩）刺激的体感诱发电位（SERs），并与48例正常受试者记录的结果进行比较。轻叩刺激施加于双侧手指、手掌和前臂。另一方面，对5例患者记录了对电刺激的SERs，并将其与对机械刺激的SERs进行比较。1. 48例手指机械刺激SERs中有32例部分波峰缺失，其余16例中有10例波峰潜伏期异常延长。另一方面，27例前臂机械刺激SERs中只有2例异常。2. 手指有麻木感的患者记录的35例SERs中有27例部分波峰缺失，其余8例波峰潜伏期异常延长。3. 关于SERs波峰缺失情况，P2和N2波峰比N3和P4波峰更常缺失。4. 职业性振动病患者SERs的波峰潜伏期异常延长。患者与对照组波峰潜伏期差异有统计学意义。5. 对5例患者记录了10例机械刺激SERs和10例电刺激SERs。10例机械刺激SERs中有9例异常，而10例电刺激SERs中仅观察到2例异常。6. 基于对机械刺激的异常SERs与患者手指麻木感之间的密切关系，得出职业性振动病的感觉障碍是由于周围神经病变所致的结论。因此，对机械刺激的SERs可用于检测周围神经病变引起的一些局部感觉异常。
