Müller H E, Seidler D
Zentralbl Bakteriol Orig A. 1975 Jan;230(1):51-8.
Investigating sera from pigs with chronic E. rhusiopathiae infection relative gamma-globulin values, agglutination titers, and neuraminidase-neutralizing humoral antibodies were determined at the 12th and 15th, 11th and 14th, and 3rd and 6th month after infection. We found increasing gammaglobulin values and increasing neuraminidase neutralizing antibodies but decreasing agglutination titers. Few animals don't have antibodies against neuraminidase and died during the observation period. Furthermore immunodiffusion test demonstrated precipitating lines of antibodies against living E. rhusiopathiae cells and active neuraminidase. No or very weak bands were observed against heat killed cells and heat-inactivated enzyme.