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乳酸脱氢酶在小鼠乳腺癌细胞中的超微结构定位

Ultrastructural localization of lactic dehydrogenase in mouse mammary carcinoma cells.

作者信息

Ghosh B C, Ghosh L, Boarini M, Newson B, Das Gupta T K

出版信息

J Surg Oncol. 1979 Dec;12(4):327-32. doi: 10.1002/jso.2930120406.

DOI:10.1002/jso.2930120406
PMID:522489
Abstract

Electron microscopic study of lactic dehydrogenase (LDH) was carried out in C3H mouse mammary carcinoma cells. Scattered cytoplasmic LDH granules were noted as well as around mitochondria and nuclear membrane. Control studies with normal breast tissues failed to show any activity. This observation suggests that LDH plays an important role in C3H mammary carcinoma and may be of use as an additional marker.

摘要

对C3H小鼠乳腺癌细胞进行了乳酸脱氢酶（LDH）的电子显微镜研究。观察到散在的细胞质LDH颗粒以及线粒体和核膜周围的颗粒。对正常乳腺组织的对照研究未显示任何活性。该观察结果表明，LDH在C3H乳腺癌中起重要作用，可能用作额外的标志物。

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