The effect of ACTH and cortisone on basement membrane in relation to the embryological origin of the epithelium.

The changes of intensity of PAS reaction in basement membranes of epithelial cells derived from 3 different germ layers in rats after treatment with ACTH and cortisone were observed. After treatment with cortisone an increase of PAS reaction in all investigated basement membranes was observed. Influence of cortisone on all basement membranes was independent of the embryological origin. The results after treatment with ACTH were not uniform.