Grudzińska B, Kasperek S, Majchrzak R
Neurol Neurochir Pol. 1979;13(5):491-6.
Seven cases of SLE with concomitant neurological syndromes are reported. In 2 cases brain stroke with right-sided hemiplegia and aphasia developed, in the remaining cases brain-stem stroke with subarachnoid haemorrhage, progressive hemiparesis and signs of intracranial hypertension, chorea, status epilepticus in terminal uraemia were observed. In one case myasthenia coexisted. Severe neurological syndromes were preceded by signs of involvement of other organs and in most cases by low-grade signs of central nervous system involvement. Treatment with corticosteroids and immunosuppressants resulted in significant improvement without complete remission. A retrospective survey of clinical material showed that modern therapeutic methods have improved the prognosis in systemic lupus erythematosus independently of central nervous system involvement.
报告了7例伴有神经综合征的系统性红斑狼疮（SLE）病例。其中2例发生了伴有右侧偏瘫和失语的脑卒，其余病例观察到伴有蛛网膜下腔出血的脑干卒中、进行性偏瘫和颅内高压体征、舞蹈病、终末期尿毒症时的癫痫持续状态。1例合并重症肌无力。严重神经综合征之前有其他器官受累的体征，且大多数情况下有中枢神经系统轻度受累的体征。使用皮质类固醇和免疫抑制剂治疗后有显著改善，但未完全缓解。对临床资料的回顾性调查显示，现代治疗方法改善了系统性红斑狼疮的预后，与中枢神经系统受累无关。
