Naruse S, Horikawa Y, Yamaki T, Odake G, Tohyama M, Hirakawa K
No Shinkei Geka. 1979 Oct;7(10):1005-10.
A case of medulloblastoma with extracranial metastases was reported. A 20-year-old woman was operated on for cerebellar medulloblastoma twice during the past 5 years and a half. Two years after the second operation, she revealed the metastases to the cervical, axillar and inguinal lymphnodes, and to the skeletal system, such as the skull, scapula, humerus, sternum, spine, pelvis and femur. The cause of extracranial metastases in the very core in this case. While the tumor was located deep in the cerebellar hemisphere at the first operation, it spread over the cerebellar surface at the after the second operation, so that the tumor cells became infiltrative to the dura mater. Thus through lymphatic and circulatory system extracranial metastases occurred. The location of the tumor seems important in this case.
报告了一例髓母细胞瘤伴颅外转移的病例。一名20岁女性在过去五年半内因小脑髓母细胞瘤接受了两次手术。第二次手术后两年,她出现了颈部、腋窝和腹股沟淋巴结以及骨骼系统(如颅骨、肩胛骨、肱骨、胸骨、脊柱、骨盆和股骨)的转移。在这种情况下,颅外转移的核心原因。第一次手术时肿瘤位于小脑半球深部,第二次手术后肿瘤扩散至小脑表面,致使肿瘤细胞浸润至硬脑膜。因此,通过淋巴和循环系统发生了颅外转移。在这种情况下,肿瘤的位置似乎很重要。