Białowas J, Stachowiak M, Jurkowski K, Dytkowska A
Pol J Pharmacol Pharm. 1979 Jul-Aug;31(4):325-35.
The effect of intragastric glucose infusion (1.5 g per rat) to sated rats on the catecholamine content in the medial basal and lateral hypothalamic regions and in the nuclei of the amygdaloid body was investigated. The effect of glucose overloading on the noradrenaline (NA) and dopamine (DA) content in the ventromedial (VMH) and arcuate hypothalamic nuclei was also studied in rats deprived of food for 48 hr. Glucose administration to rats fed ad lib. resulted in an increase in NA in the VMH and a decrease in DA in the central nucleus of the amygdaloid body. In fasted animals glucose overloading partially reversed the changes of NA concentration in the arcuate nucleus produced by starvation, whereas in the VMH glucose was not effective in producing any changes of catecholamine content. Possible interrelations between the amygdala and hypothalamus in respect to the role of catecholamines in the regulation of food intake are discussed.
研究了向饱足大鼠胃内输注葡萄糖（每只大鼠1.5克）对下丘脑内侧基底部、外侧区以及杏仁核各核团中儿茶酚胺含量的影响。还研究了对禁食48小时的大鼠进行葡萄糖超载处理后，腹内侧下丘脑核（VMH）和弓状核中去甲肾上腺素（NA）和多巴胺（DA）含量的变化。对自由进食的大鼠给予葡萄糖后，VMH中的NA增加，杏仁中央核中的DA减少。在禁食动物中，葡萄糖超载部分逆转了饥饿引起的弓状核中NA浓度的变化，而在VMH中，葡萄糖对儿茶酚胺含量没有产生任何影响。本文讨论了杏仁核与下丘脑之间在儿茶酚胺对食物摄入调节作用方面可能存在的相互关系。
