播散性血管内凝血合并先天性神经母细胞瘤
Disseminated intravascular coagulation in association with congenital neuroblastoma.
作者信息
Thompson E N, Bosley A
出版信息
Postgrad Med J. 1979 Nov;55(649):814-7. doi: 10.1136/pgmj.55.649.814.
Abstract
A 3-month-old infant with neuroblastoma complicated by progressive depletion of coagulation factors and a microangiopathic haemolytic anaemia is described. Specific anti-tumour therapy corrected the haemorrhagic defect on 2 occasions, but did not affect tumour bulk significantly, although a fall in urinary vanillyl-mandelic acid was seen. The rarity of this association and the possible underlying mechanisms are discussed.
摘要
本文描述了一名3个月大的神经母细胞瘤婴儿，其并发凝血因子进行性消耗和微血管病性溶血性贫血。特异性抗肿瘤治疗曾两次纠正出血缺陷，但虽可见尿香草扁桃酸下降，但对肿瘤体积影响不大。本文讨论了这种关联的罕见性及可能的潜在机制。
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