Kounis N G
Postgrad Med J. 1979 Nov;55(649):832-5. doi: 10.1136/pgmj.55.649.832.
Three patients who developed a distinctive form of ventricular tachycardia with oscillating QRS axis, while they were receiving drugs known to prolong the repolarization time are described. In one of the patients suffering from psychiatric illness and receiving psychotropic drugs the arrhythmia was fatal. It is postulated that the tendency to this arrhythmia was augmented by repeated electric counter shocks and negative bathmotropic drugs. Functional factors may contribute to the pathogenesis of this arrhythmia which seems to constitute an entity.
本文描述了三名患者,他们在接受已知可延长复极时间的药物治疗时,出现了一种独特形式的室性心动过速,其QRS轴呈振荡状。其中一名患有精神疾病并正在接受精神药物治疗的患者,该心律失常是致命的。据推测,反复的电除颤和负性变力性药物会增加发生这种心律失常的倾向。功能因素可能促成了这种似乎是一种独立病症的心律失常的发病机制。