Grotte G, Hagberg S, Lännergren K, Löhr G, Nettelblad S C, Werkmäster K
Prog Pediatr Surg. 1979;13:231-8.
The mortality of children with posterolateral diaphragmatic hernia (PDH) is mainly dependent upon the degree of lung hypoplasia. Other less significant factors are dysmaturity, associated anomalies, infection and haemorrhages. Children with grave cyanosis from PDH immediately after birth have a poor prognosis due to persistent foetal circulation with pulmonary vascular hypertension and right-left shunting. A better understanding and treatment of this persistent foetal circulation may considerably improve the surgical mortality, though in some cases the lung hypoplasia may be too far advanced.
后外侧膈疝(PDH)患儿的死亡率主要取决于肺发育不全的程度。其他不太重要的因素包括发育不成熟、相关畸形、感染和出血。出生后即因PDH出现严重紫绀的患儿,由于持续的胎儿循环伴肺血管高压和右向左分流,预后较差。对这种持续胎儿循环的更好理解和治疗可能会显著降低手术死亡率,尽管在某些情况下肺发育不全可能已非常严重。