• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

[儿童颅内压的连续监测及神经重症监护的新进展]

[Continuous monitoring of intracranial pressure and new aspects of neurologic intensive care for children].

作者信息

Pfenninger J, Kaiser G

出版信息

Schweiz Med Wochenschr. 1979 Nov 17;109(44):1693-9.

PMID:524100
Abstract

A new concept of neurointensive care is presented which is based on earily measured parameters such as intracranial pressure (ICP), mean arterial pressure (MAP) and cerebral perfusion pressure (CPP) (CPP = MAP - ICP). ICP should preferably be measured by a subarachnoid hollow screw (Richmond screw). Of chief importance in neurointensive care (after adequate neurodiagnosis) is the avoidance or treatment of cerebral edema and maintenance of sufficient CPP, which should be above 50 mm Hg in older children. This is achieved by controlled hyperventilation under curare, generous oxygenation, control of body temperature, dexamethasone and possibly barbiturates in very high doses (phenobarbital and thiopentone). This kind of neurointensive care should be administered in all types of severe CNS accidents which are followed by substantial cerebral edema (head injuries, near drowning, Reye's syndrome, hypoxic encephalopathy, encephalitis, meningitis and intracranial bleeding). To obtain the indication for ICP monitoring, the depth of the disturbance of consciousness is measured by the Glasgow Coma Scale. Children with the aforementioned affections and a Glasgow Coma Scale below 6 to 8 should be treated as outlined above. The data published in the literature and our own experience point very much in this direction, especially for severe head injury, Reye's syndrome and near drowning.

摘要

提出了一种新的神经重症监护概念,该概念基于早期测量的参数,如颅内压(ICP)、平均动脉压(MAP)和脑灌注压(CPP)(CPP = MAP - ICP)。ICP最好通过蛛网膜下腔空心螺钉(里士满螺钉)进行测量。在神经重症监护中(在进行充分的神经诊断后),最重要的是避免或治疗脑水肿并维持足够的CPP,年龄较大的儿童CPP应高于50 mmHg。这可通过在箭毒作用下进行控制性过度通气、充分给氧、控制体温、使用地塞米松以及可能使用高剂量的巴比妥类药物(苯巴比妥和硫喷妥钠)来实现。这种神经重症监护应适用于所有类型的严重中枢神经系统意外事故,这些事故会继发严重脑水肿(头部损伤、近乎溺水、瑞氏综合征、缺氧性脑病、脑炎、脑膜炎和颅内出血)。为了获得ICP监测的指征,通过格拉斯哥昏迷量表来测量意识障碍的深度。患有上述疾病且格拉斯哥昏迷量表低于6至8分的儿童应按上述方法进行治疗。文献中发表的数据以及我们自己的经验都非常支持这一方向,尤其是对于严重头部损伤、瑞氏综合征和近乎溺水的情况。

相似文献

1
[Continuous monitoring of intracranial pressure and new aspects of neurologic intensive care for children].[儿童颅内压的连续监测及神经重症监护的新进展]
Schweiz Med Wochenschr. 1979 Nov 17;109(44):1693-9.
2
[Triage and treatment in juvenile drowning accidents].[青少年溺水事故的分诊与治疗]
Schweiz Med Wochenschr. 1981 Jun 13;111(24):878-84.
3
Continuous cerebral compliance monitoring in severe head injury: its relationship with intracranial pressure and cerebral perfusion pressure.重型颅脑损伤中脑顺应性的连续监测:其与颅内压和脑灌注压的关系。
Acta Neurochir (Wien). 2005 Jul;147(7):707-13; discussion 713. doi: 10.1007/s00701-005-0537-z. Epub 2005 May 30.
4
Prolonged continuous monitoring of intracranial pressure in severe Reye's syndrome.对重症瑞氏综合征患者进行长时间的颅内压连续监测。
Pediatrics. 1977 Apr;59(4):595-605.
5
[Intensive care of patients in a coma following severe craniocerebral injury].[重型颅脑损伤后昏迷患者的重症监护]
Lijec Vjesn. 1995 Jun;117 Suppl 2:59-61.
6
Barbiturate therapy for patients with refractory intracranial hypertension following severe traumatic brain injury: its effects on tissue oxygenation, brain temperature and autoregulation.巴比妥类药物治疗重度创伤性脑损伤后难治性颅内高压患者:对组织氧合、脑温及自动调节的影响
J Clin Neurosci. 2008 Feb;15(2):143-8. doi: 10.1016/j.jocn.2006.08.014. Epub 2007 Nov 7.
7
Barbiturate infusion for intractable intracranial hypertension and its effect on brain oxygenation.巴比妥类药物输注治疗顽固性颅内高压及其对脑氧合的影响。
Neurosurgery. 2008 Nov;63(5):880-6; discussion 886-7. doi: 10.1227/01.NEU.0000327882.10629.06.
8
Survey of critical care management of severe traumatic head injury in Israel.以色列严重创伤性脑损伤重症监护管理调查。
Childs Nerv Syst. 2002 Aug;18(8):375-9. doi: 10.1007/s00381-002-0613-0. Epub 2002 Jul 23.
9
[Intracranial pressure in comatose meningitis and encephalitis in children].[儿童昏迷性脑膜炎和脑炎的颅内压]
Pediatrie. 1988;43(6):539-44.
10
Cerebral perfusion pressure between 50 and 60 mm Hg may be beneficial in head-injured patients: a computerized secondary insult monitoring study.50至60毫米汞柱的脑灌注压可能对头外伤患者有益:一项计算机化二次损伤监测研究。
Neurosurgery. 2005 May;56(5):962-71; discussion 962-71.

引用本文的文献

1
Treatment and outcome of the severely head injured child.
Intensive Care Med. 1983;9(1):13-6. doi: 10.1007/BF01693699.