Babiarz B S, Wee E L, Zimmerman E F
Teratology. 1979 Oct;20(2):249-78. doi: 10.1002/tera.1420200210.
The process of palate shelf elevation has been analyzed by light microscopy in mouse embryos cultured in vitro. The observations presented correlate changes in cell shape and orientation in the palate with the morphogenetic movement of the shelf. These studies suggest that in addition to any physical-chemical force elevating the shelf an active contraction of specific palate cells could also aid the process. Contribution to elevation could be derived from masses of contracting cells from the previously described non-muscle contractile systems in posterior (region 2) and mid-anterior (region 3) palate as well as other peripheral mesenchymal cells. Finally, elongation and contraction of the tongue side epithelial cells may also play a role in palate elevation.
通过光学显微镜对体外培养的小鼠胚胎腭板抬高过程进行了分析。所呈现的观察结果将腭部细胞形状和方向的变化与腭板的形态发生运动联系起来。这些研究表明，除了任何抬高腭板的物理化学力之外，特定腭部细胞的主动收缩也可能有助于这一过程。抬高作用可能源于先前描述的腭部后部（区域2）和中前部（区域3）非肌肉收缩系统的收缩细胞团以及其他外周间充质细胞。最后，舌侧上皮细胞的伸长和收缩也可能在腭板抬高过程中发挥作用。
