Estanol B, Rodriguez A, Conte G, Aleman J M, Loyo M, Pizzuto J
Stroke. 1979 Nov-Dec;10(6):680-4. doi: 10.1161/01.str.10.6.680.
Twenty women of child-bearing age with intracranial venous thrombosis are reported. Thirteen developed thrombosis post-partum; 6 while on oral contraceptives. In one patient no cause was found. All diagnoses were confirmed by carotid angiography and in 10 out of 14 patients laboratory data indicated a hypercoagulable state. Coagulation studies were performed in 14 normal puerperal women, matched by age, who served as controls. No statistical differences was found between thrombotic and control groups. Radiologic signs of sino-venous occlusion are reviewed. Conservative treatment with anti-edematous agents, anticonvulsants and antiplatelet aggregants is advocated.
本文报告了20例育龄期颅内静脉血栓形成的女性患者。其中13例在产后发生血栓形成;6例在服用口服避孕药期间发病。1例患者未发现病因。所有诊断均经颈动脉血管造影证实,14例患者中的10例实验室数据显示存在高凝状态。对14名年龄匹配的正常产后女性进行了凝血研究作为对照。血栓形成组和对照组之间未发现统计学差异。本文还回顾了静脉窦闭塞的放射学征象。提倡使用抗水肿药物、抗惊厥药物和抗血小板聚集剂进行保守治疗。