Khristoforov L, Peshkov I, Ivancheva L
Vet Med Nauki. 1979;16(3):3-7.
Investigations were carried out after a micromethod for RCB formulation and standardization proposed by the authors used as the basic method of neorickettsiosis diagnositcs. In the course of 4 years 3614 serums of healthy animals and 289 serums of sheep, cattle and swine suffering from neorickettsiosis were investigated. It was established that the titre of complement binding antibodies in neorickettsiosis is stable. Variations are rarely observed and they are of low titre grade. Specific neorickettsiosis titres in sheep, cattle and swine are considerably high (1:128 to 1:256 and 1:512). The diagnostic value of low titres is in correlation with the phase of the infection process development and can be assessed only by following the dynamics of complement binding antibodies.
在作者提出的一种用于立氏立克次体病（neorickettsiosis）诊断的基本方法——立氏立克次体（RCB）制剂和标准化的微量方法被用作基本方法之后，展开了调查研究。在4年期间，对3614份健康动物血清以及289份患有立氏立克次体病的绵羊、牛和猪的血清进行了调查。结果确定，立氏立克次体病中补体结合抗体的滴度是稳定的。很少观察到变化，且变化的滴度等级较低。绵羊、牛和猪中立氏立克次体病的特异性滴度相当高（1:128至1:256以及1:512）。低滴度的诊断价值与感染过程发展阶段相关，并且只能通过追踪补体结合抗体的动态变化来评估。
