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[肾性骨营养不良晚期的甲状旁腺次全切除术]

[Subtotal parathyroidectomy in the advanced stages of renal osteodystrophy].

作者信息

Giertler R, Pfann B, Scheler U, Schmidt U, Scheibner K

出版信息

Z Urol Nephrol. 1979 Jul;72(12):523-30.

PMID:525073
Abstract

In 7 haemodialysis patients with progressing renal osteopathy a partly subtotal, partly total parathyroidectomy was carried out. Postoperatively in all cases a clinical improvement developed, which, however, in part was only transient. The laboratory parameters showed a rapid tendency to normalisation, the X-ray diagnostic finding and the bone mineral content remained essentially unchanged, also the histological skeletal findings. The results are compiled in form of tables. The value of the diagnostic measures which should precede a subtotal parathyroidectomy is discussed. At present the different postoperative courses apparently cannot be prospectively estimated with the help of the hitherto usual diagnostic measures. On the basis of the partly good results and of the operation risk which is to be thoroughly demanded of a haemodialysis patient it seems that after having used all conservative possibilities the surgical interventions nevertheless indicated in progressing renal osteopathy.

摘要

对7例患有进行性肾性骨病的血液透析患者进行了部分甲状旁腺次全切除术和部分甲状旁腺全切除术。术后所有病例临床症状均有改善,但部分改善仅为短暂性。实验室参数显示有迅速恢复正常的趋势,X线诊断结果、骨矿物质含量以及组织学骨骼检查结果基本保持不变。结果以表格形式汇总。讨论了在甲状旁腺次全切除术之前应采取的诊断措施的价值。目前,借助迄今常用的诊断措施,显然无法前瞻性地预估不同的术后病程。基于部分良好的结果以及对血液透析患者所要求的全面手术风险,似乎在穷尽所有保守治疗可能性之后,手术干预对于进行性肾性骨病而言仍是必要的。

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