Isono H, Shoumura S, Ishizaki N, Hayashi K, Yamahira T, Yamada S
Acta Anat (Basel). 1979;105(1):50-5. doi: 10.1159/000145106.
Electron-microscopic studies were made on the parathyroid gland of cadmium-treated mice. Most chief cells in treated mice were rich in free ribosomes and secretory granules compared to the control mice. In the parathyroid gland after 3 and 4 weeks of administration of cadmium, interdigitations between adjacent chief cells became more complex than in the control mice. In most chief cells of the parathyroid gland after 2, 3 and 4 weeks of administration of cadmium, the Golgi complexes associated with numerous prosecretory granules were better developed than in the control mice. These ultrastructural appearances suggest that parathyroid gland cellular activity was stimulated in response to cadmium treatment.
对镉处理小鼠的甲状旁腺进行了电子显微镜研究。与对照小鼠相比，经处理的小鼠中大多数主细胞富含游离核糖体和分泌颗粒。在给予镉3周和4周后的甲状旁腺中，相邻主细胞之间的指状交叉比对照小鼠更为复杂。在给予镉2周、3周和4周后的甲状旁腺大多数主细胞中，与大量前分泌颗粒相关的高尔基体复合体比对照小鼠发育得更好。这些超微结构表现表明，甲状旁腺细胞活性因镉处理而受到刺激。
