Orlander J, Kiessling K H, Larsson L
Acta Physiol Scand. 1979 Sep;107(1):39-46. doi: 10.1111/j.1748-1716.1979.tb06440.x.
Smokers and nonsmokers of a homogeneous population of sedentary men have been compared with respect to skeletal muscle (vastus lateralis) morphological, metabolic and functional characteristics. The percentage type I fibres was lower and that of type IIB fibres higher in the smokers. Fibre areas were almost equal in the two groups. Muscle oxidative capacity was lowered in the smokers, as judged from decreased mitochondrial enzyme activities and a lowered fibrillar space mitochondrial volume fraction. Isometric and dynamic strengths were lower in the smokers, except at the highest velocity of movement studied. Dynamic strengths expressed in relation to isometric strength were similar at all velocities except the highest, where the smokers were relatively stronger. Muscular endurance, measured in short-term isometric and dynamic tests, was not different. It is suggested that the lowered muscle oxidative capacity and strength in the smokers may be partly a consequence of the different fibre type distribution. A possibly lower physical activity level, and tobacco smoke constituents (e.g. carbon monoxide) may also be instrumental. It is not clear whether the different fibre type distribution in the smokers is an effect of smoking per se, or if background factors are responsible.
对一群久坐不动的男性中吸烟者和非吸烟者的骨骼肌（股外侧肌）形态、代谢及功能特征进行了比较。吸烟者中I型纤维百分比更低，IIB型纤维百分比更高。两组的纤维面积几乎相等。从线粒体酶活性降低和肌原纤维间隙线粒体体积分数降低判断，吸烟者的肌肉氧化能力降低。吸烟者的等长和动态力量较低，但在所研究的最高运动速度下除外。除最高速度外，所有速度下动态力量与等长力量的比值相似，在最高速度下吸烟者相对更强。在短期等长和动态测试中测得的肌肉耐力并无差异。提示吸烟者肌肉氧化能力和力量降低可能部分是不同纤维类型分布的结果。可能较低的身体活动水平以及烟草烟雾成分（如一氧化碳）也可能起作用。尚不清楚吸烟者中不同的纤维类型分布是吸烟本身的影响，还是由背景因素所致。
