Schneider W, McCarty L J
Folia Haematol Int Mag Klin Morphol Blutforsch. 1975;102(3):318-24.
The freezing and storing of glycerol protected red cells allows the present 20---40 day limitation of red cell storage to be indefinitely lengthened. Although frozen thawed cells are more expensive to prepare than ordinary packed cells, the longer shelf-life of the red cells, the reduced risk of hepatitis transmission, and the reduction of immunization against leuko- and thrombocytes, are all advantages which out-weighed this additional cost. To effect an increase in their use, frozen thawed cells could be distributed from central blood banks to hospitals were they would be stored until needed for transfusion. Thawing and washing would necessarily be done by the hospital blood bank personnel.
甘油保护红细胞的冷冻和储存能使目前红细胞20至40天的储存期限无限延长。尽管冻融红细胞的制备成本比普通浓缩红细胞高，但红细胞更长的保质期、降低的肝炎传播风险以及减少针对白细胞和血小板的免疫反应，这些优势足以抵消额外的成本。为了增加其使用量，冻融红细胞可从中心血库分发至医院，在医院储存直至输血需要时使用。解冻和洗涤工作必然由医院血库工作人员完成。
