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脑提取物的行为诱导:两种程序的比较。

Behavior induction by brain extracts: a comparison of two procedures.

作者信息

Rosenblatt F

出版信息

Proc Natl Acad Sci U S A. 1969 Oct;64(2):661-8. doi: 10.1073/pnas.64.2.661.

DOI:10.1073/pnas.64.2.661
PMID:5261041
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC223395/
Abstract

Induction of behavior by chemical extracts of trained rat brain has been observed in two types of choice situations. (1) In a symmetric (left/right) choice situation, the induced bias may be either positively or negatively related to that learned by the donors, depending strongly upon dosage and the exact experimental conditions. This makes the effect unstable and difficult to replicate with this procedure. Inversion effects appear to predominate in the observed dosage range. (2) In an asymmetric (two-chamber) choice situation, differing in operant tasks, wall colors, and other cues, a consistently positive effect with a simpler dose dependence was observed. The difference between these two cases is attributed to the lack of specific stimuli identifying the behavioral choices in the symmetric situation, and the abundance of specific stimulus cues in the asymmetric case.

摘要

在两种选择情境中观察到了经训练的大鼠脑化学提取物对行为的诱导作用。(1)在对称(左/右)选择情境中,诱导偏差可能与供体所学习的偏差呈正相关或负相关,这在很大程度上取决于剂量和确切的实验条件。这使得该效应不稳定,难以用此程序重复。在观察到的剂量范围内,反转效应似乎占主导。(2)在不对称(双室)选择情境中,操作任务、墙壁颜色和其他线索不同,观察到了具有更简单剂量依赖性的一致正向效应。这两种情况之间的差异归因于对称情境中缺乏识别行为选择的特定刺激,以及不对称情况下存在大量特定刺激线索。

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引用本文的文献

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本文引用的文献

1
Behavioral assay procedures for transfer of learned behavior by brain extracts, ii.用于通过脑提取物转移习得行为的行为测定程序,ii。
Proc Natl Acad Sci U S A. 1966 Dec;56(6):1683-8. doi: 10.1073/pnas.56.6.1683.
2
Transfer of habituation by material extracted from brain.
Nature. 1965 Jul 17;207(994):301-2. doi: 10.1038/207301a0.
3
The transfer of learned behavior from trained to untrained rats by means of brain extracts. II.通过脑提取物将习得行为从受过训练的大鼠转移到未受过训练的大鼠。二。
Proc Natl Acad Sci U S A. 1966 Apr;55(4):787-92. doi: 10.1073/pnas.55.4.787.