急性淋巴细胞白血病中使用阿糖胞苷和L-天冬酰胺酶进行缓解诱导
Remission induction with cytosine arabinoside and L-asparaginase in acute lymphoblastic leukaemia.
作者信息
McElwain T J, Hardisty R M
出版信息
Br Med J. 1969 Dec 6;4(5683):596-8. doi: 10.1136/bmj.4.5683.596.
Abstract
Nine patients with acute lymphoblastic leukaemia in relapse were treated with a course of cytosine arabinoside followed immediately by a course of L-asparaginase. Eight patients achieved complete remission of their disease. This combination of drugs is sufficiently effective to suggest that further trial is needed. It is possible that the combination has a synergistic effect.
摘要
9例急性淋巴细胞白血病复发患者接受了一个疗程的阿糖胞苷治疗，随后立即接受一个疗程的L-天冬酰胺酶治疗。8例患者疾病完全缓解。这种药物组合疗效显著，表明有必要进一步试验。该组合可能具有协同作用。
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本文引用的文献
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Drug effect in acute leukemia.药物在急性白血病中的作用。
J Clin Invest. 1969 Jun;48(6):1124-30. doi: 10.1172/JCI106069.
3
Arabinosyl cytosine: a useful agent in the treatment of acute leukemia in adults.阿糖胞苷：治疗成人急性白血病的有效药物。
Blood. 1968 Oct;32(4):507-23.
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