Al-Sheikhly F, Mutalib A A
Avian Dis. 1979 Jul-Sep;23(3):763-7.
Eighteen outbreaks of inclusion body hepatitis (IBH) were identified in broiler chickens in Baghdad in 1977 and 1978. The disease was seen mainly in 4-to-6-week-old broiler chickens. The mortality rate did not exceed 1% in any outbreak investigated. The most common gross findings were stellate or punctiform hemorrhagic areas in markedly fatty livers. Noticed in many cases were enlarged and pale kidneys, hemorrhagic lesions in the skeletal muscles, and pale fattened bone marrow. Histological examination of tissues revealed fat droplets and intranuclear inclusion bodies in degenerated liver cells. Eosinophilic inclusion bodies were seen in all cases. Only five cases had basophilic inclusions along with the eosinophilic ones. The etiologic agent was isolated on chorioallantoic membrane (CAM) of 12-day-old embryonated chicken eggs. The disease was produced experimentally in 4-week-old chicks using infected CAM suspension.
1977年和1978年在巴格达的肉鸡中发现了18起包涵体肝炎（IBH）疫情。该病主要见于4至6周龄的肉鸡。在任何调查的疫情中，死亡率均未超过1%。最常见的大体病变是明显脂肪变性的肝脏出现星状或点状出血区。许多病例还可见肾脏肿大、苍白，骨骼肌有出血性病变，骨髓苍白且增粗。组织学检查显示，变性肝细胞中有脂肪滴和核内包涵体。所有病例均可见嗜酸性包涵体。只有5例同时有嗜碱性包涵体和嗜酸性包涵体。病原体是从12日龄鸡胚的绒毛尿囊膜（CAM）上分离出来的。用感染的CAM悬液在4周龄雏鸡中进行了该病的实验性诱发。
