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正常受试者服用诺米芬辛后的皮质醇分泌情况。

Cortisol secretion following nomifensine administration in normal subjects.

作者信息

Alagna S, Masala A

出版信息

Biomedicine. 1979 Nov;31(7):189-91.

PMID:526541
Abstract

The effects of the oral administration of nomifensine, which inhibits endogenous cathecolamine re-uptake, on secretion of prolactin and cortisol were investigated in 12 normal subjects. In all the volunteers, a significant decrease of prolactin levels was observed following nomifensine administration. Cortisol levels were unaffected by this pharmacological treatment. The role of hypothalamic dopaminergic inhibitory system on ACTH-cortisol axis is discussed.

摘要

在12名正常受试者中研究了口服抑制内源性儿茶酚胺再摄取的诺米芬辛对催乳素和皮质醇分泌的影响。在所有志愿者中,服用诺米芬辛后观察到催乳素水平显著下降。这种药物治疗对皮质醇水平没有影响。本文讨论了下丘脑多巴胺能抑制系统在促肾上腺皮质激素-皮质醇轴上的作用。

相似文献

1
Cortisol secretion following nomifensine administration in normal subjects.正常受试者服用诺米芬辛后的皮质醇分泌情况。
Biomedicine. 1979 Nov;31(7):189-91.
2
Inhibition of prolactin secretion by nomifensine in man.
Clin Endocrinol (Oxf). 1980 Mar;12(3):237-41. doi: 10.1111/j.1365-2265.1980.tb02705.x.
3
Pharmacodynamics of nomifensine: a review of studies in healthy subjects.
J Clin Psychiatry. 1984 Apr;45(4 Pt 2):33-8.
4
Drug-induced alterations of the hypothalamus-hypophysis axis.药物引起的下丘脑 - 垂体轴改变。
Acta Psychiatr Belg. 1980 Sep-Oct;80(5):619-37.
5
Effects of nomifensine on growth hormone and prolactin secretion in normal subjects and in pathological hyperprolactinemia.诺米芬辛对正常受试者及病理性高催乳素血症患者生长激素和催乳素分泌的影响。
J Clin Endocrinol Metab. 1982 Jun;54(6):1125-8. doi: 10.1210/jcem-54-6-1125.
6
The effect of nomifensine on thyroid-stimulating hormone (TSH) in normal and hyperprolactinemic subjects.
Neuroendocrinology. 1983 Dec;37(6):406-10. doi: 10.1159/000123584.
7
Effect of nomifensine on cortisol, prolactin and biogenic amines in neurotic depressed patients.诺米芬辛对神经症性抑郁症患者皮质醇、催乳素和生物胺的影响。
Neuropsychobiology. 1983;10(4):209-12. doi: 10.1159/000118013.
8
Effect of a dopaminergic drug on LH, FSH and prolactin levels in PCO syndrome.一种多巴胺能药物对多囊卵巢综合征患者促黄体生成素、促卵泡生成素和催乳素水平的影响。
Acta Eur Fertil. 1981 Sep;12(3):295-7.
9
Failure of nomifensine to reduce serum prolactin levels in patients with hepatic encephalopathy.诺米芬辛未能降低肝性脑病患者的血清催乳素水平。
J Endocrinol Invest. 1985 Feb;8(1):25-9. doi: 10.1007/BF03350631.
10
[Influence of administration of pyridoxine on circadian rhythm of plasma ACTH, cortisol prolactin and somatotropin in normal subjects].[吡哆醇给药对正常受试者血浆促肾上腺皮质激素、皮质醇、催乳素和生长激素昼夜节律的影响]
Boll Soc Ital Biol Sper. 1984 Feb 28;60(2):273-8.

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