Bremond A, Dargent D, Frappart L, Beau G
Bull Cancer. 1979;66(4):455-9.
The authors have studied by step serial sectioning 312 cervix the most obtained by cold knife conization. They have studied too, the frequency of inadequate resection (i.e. non in sano conization) and clinically occult invasion according to the age of patients. Conization is adequate for the treatment of 70 per cent of women less than 30 years of age. But after 50 it is sufficient in only 22 per cent of the patients. Conization must be performed in most cases of grade III to V cervical smear (according to Papanicolaou's classification). The cervical cone must be studied by serial sectioning (every 500 microns). According to the result of this study the treatment must be selected : conization for in situ carcinoma resected in sano, simple hysterectomy for in situ carcinoma not resected in situ and Wertheim type operation for invasive carcinoma.
作者通过对312例经冷刀锥切术获取的宫颈组织进行连续切片研究。他们还根据患者年龄，研究了切除不充分（即锥切不完全）和临床隐匿性浸润的发生率。锥切术适用于70%年龄小于30岁的女性的治疗。但50岁以后，仅22%的患者锥切就足够了。在大多数III至V级宫颈涂片（根据巴氏分类法）的病例中必须进行锥切术。宫颈锥切组织必须进行连续切片研究（每隔500微米）。根据这项研究结果，必须选择相应的治疗方法：原位癌切除彻底者行锥切术，原位癌切除不彻底者行单纯子宫切除术，浸润癌行韦特海姆式手术。
